• Artículo
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      Endogenous topoisomerase II-mediated DNA breaks drive thymic cancer predisposition linked to ATM deficiency 

      Álvarez Quilón, Alejandro; Terrón Bautista, José; Delgado Sainz, Irene; Serrano Benítez, Almudena; Romero Granados, Rocío; Martínez García, Pedro Manuel; Jimeno González, Silvia; Bernal Lozano, Cristina; Quintero, Cristina; García Quintanilla, Lourdes; Cortés Ledesma, Felipe (Springer Nature, 2020)
      The ATM kinase is a master regulator of the DNA damage response to double-strand breaks (DSBs) and a well-established ...
    • Tesis Doctoral
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      Global Dynamics of Topoisomerase II Activity 

      Terrón Bautista, José (2022-04-22)
      DNA topoisomerases are key enzymes in charge of solving topological problems that arise from essential processes of DNA ...
    • Artículo
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      Topoisomerase IIα represses transcription by enforcing promoter-proximal pausing 

      Herrero Ruiz, Andrés M.; Martínez García, Pedro Manuel; Terrón Bautista, José; Millán Zambrano, Gonzalo; Lieberman, Jenna Ariel; Jimeno González, Silvia; Cortés Ledesma, Felipe (Elsevier, 2021)
      Accumulation of topological stress in the form of DNA supercoiling is inherent to the advance of RNA polymerase II (Pol ...